Quetiapine-induced galactorrhea with normal prolactin level in an adult female patient.

To the Editor: Quetiapine is an atypical antipsychotic agent with less propensity than other atypical antipsychotics to induce antipsychotic-associated hyperprolactinemia in standard recommended therapeutic dosages, and when it does induce the condition at all, the rise in serum prolactin level is only transient. Accordingly, quetiapine has been recommended as an alternative in patients who develop galactorrhea associated with other antipsychotics. However, hyperprolactinemia with related side effects may rarely be encountered in a few susceptible individuals. We describe a case of quetiapine-induced galactorrhea without an increase in blood prolactin level in an adult female patient. We then discuss the implications of quetiapine with respect to such an adverse effect.